ISSN 0189-1774
 
2026, Vol: 24, Issue: 2
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Original Article
Online Published: 20 May 2024
 


Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.

Olose, O. E., Uwakwe R„ Oche M., Agomoha., Modebe I..


Abstract
Aims: To investigate the effect of the use of antipsychotic medication on patients with schizophrenia with regard to
their blood glucose profile and weight. Methods: From a sample of 209 antipsychotic naive patients with schizophrenia and an equal number of their first degree relatives matched for weight and gender, fasting blood glucose and weight were measured at baseline and repeated after four months.
Results: The mean initial and second wave fasting blood sugar for the cases were 4.24mmol/l (SD=0.36), and 5 . 2 6 m m o l /l ( S D= 0 . 6 7 ) respectively, (t=22.13, df=208, p<0.001). Among the controls, the respective values were 4 23mmol/l (SD=0.42), and 4 . 2 2 m m o l /l ( S D = 0 . 4 1 ) (t=0.86,df=208, p=0.38). The prevalence of hyperglycaemia was 12.4% for the cases with a mean weight gain of 4.06kg (SD=3.05), while for the controls the mean weight gain was 0.06kg (SD=0.51) (t=18.65, df=416, p=<0.001).
Conclusion: The use of antipsychotic agents was significantly associated with hyperglycaemia and weight gain. This is in keeping with previous reports,


 
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How to Cite this Article
Pubmed Style

Olose, E. O, M. URO, Agomoha. , I. M. Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. NJP. 2012; 10(1): 7-15.

Web Style

Olose, E. O, M. URO, Agomoha. , I. M. Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. https://nigerianjournalofpsychiatry.com/?mno=202461 [Access: June 27, 2026].

AMA (American Medical Association) Style

Olose, E. O, M. URO, Agomoha. , I. M. Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. NJP. 2012; 10(1): 7-15.


Vancouver/ICMJE Style

Olose, E. O, M. URO, Agomoha. , I. M. Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. NJP. (2012), [cited June 27, 2026]; 10(1): 7-15.


Harvard Style

Olose, E., . O., M., . U. R. O., Agomoha., . & I., . M. (2012) Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. NJP, 10 (1), 7-15.


Turabian Style

Olose, O. E., Uwakwe R„ Oche M., Agomoha., and Modebe I.. 2012. Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. Nigerian Journal of Psychiatry, 10 (1), 7-15.


Chicago Style

Olose, O. E., Uwakwe R„ Oche M., Agomoha., and Modebe I.. "Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.." Nigerian Journal of Psychiatry 10 (2012), 7-15.


MLA (The Modern Language Association) Style

Olose, O. E., Uwakwe R„ Oche M., Agomoha., and Modebe I.. "Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.." Nigerian Journal of Psychiatry 10.1 (2012), 7-15. Print.


APA (American Psychological Association) Style

Olose, E., . O., M., . U. R. O., Agomoha., . & I., . M. (2012) Hyperglycaemia and Weight Gain Among Patients With Schizophrenia Treated With Antipsychotics in Enugu Nigeria.. Nigerian Journal of Psychiatry, 10 (1), 7-15.


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